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Analytical Columns Product List

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Case Studies on the Analysis of Excipients Using HPLC (English Material)

Case Studies on the Analysis of Excipients Using HPLC (English Material)

Analysis of Pharmaceutical Excipients – What is Universal Chromatography Analysis for Complex Mixture Analysis?

Excipients are substances added for the purpose of shaping, bulking, and diluting solid formulations, and they consist of a mixture of compounds with various chemical properties. Both excipients and active ingredients need to be managed appropriately, and profiling their impurities is also important. What analytical methods are suitable for the detection and quantification of a wide range of excipients? Check out our ebook that covers analytical examples solved by Charged Aerosol Detectors (CAD). You are sure to find the excipient analysis you are looking for. This ebook (in English) includes the following information: • Excipients applicable to pharmaceutical manufacturing and their uses • What columns are effective for excipient analysis? Selection considering sample amount and hydrophobicity • How to detect excipients using Charged Aerosol Detectors (CAD) • Examples of excipient analysis in formulations using CAD and information from scientific papers

  • Analytical Equipment and Devices
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High-resolution sugar chain analysis column "GlycanPac AXR-1 column"

High-resolution sugar chain analysis column "GlycanPac AXR-1 column"

Analysis using a fluorescence detector and mass spectrometer is possible! Column with filler structure.

The "GlycanPac AXR-1 column" is a high-performance silica-based HPLC column that separates glycans based on charge, structural isomerism, and size. It can achieve high separation of biologically important glycans with unique selectivity, regardless of labeling. Additionally, analysis using fluorescence detectors and mass spectrometers is possible. 【Features】 ■ Unique selectivity based on charge, structural isomers, and size ■ Excellent separation capability for both labeled and unlabeled glycans ■ Utility of structural analysis and quantification of glycans based on high separation capability ■ Method compatibility with mass spectrometers and fluorescence detectors ■ Reliable column performance ■ Particle sizes for HPLC (3μm) and UHPLC (1.9μm) *For more details, please refer to the PDF document or feel free to contact us.

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  • Glassware and containers
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Restek Analytical LC Column "Biphenyl"

Restek Analytical LC Column "Biphenyl"

Innovation of Restek Biphenyl Column: Excellent selectivity and separation performance over 20 years.

Even after 20 years, Restek's Biphenyl column continues to support advancements in science by pursuing originality and innovation. Twenty years ago, Restek brought about innovative changes in the field of chromatography. This was the development of the Biphenyl column, a completely new approach to solving the challenges of LC separation faced by chromatographers. The Biphenyl column stands out with its unique selectivity, distinguishing it from traditional C18 columns and other phenyl columns, and due to its high separation performance, it has become an essential tool for many researchers. - Performance that surpasses C18 columns achieved through unique selectivity - Excellent separation performance for aromatic compounds and positional isomers - Ideal for method development and large-scale panel analysis

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"Poroshell 300" LC column for biopharmaceutical analysis

"Poroshell 300" LC column for biopharmaceutical analysis

In addition to protein separation for analysis, it can also be used for LC/MS separation with ammonia-containing mobile phases!

The "Poroshell 300" is an ideal LC column for the analysis of biopharmaceuticals, designed for the rapid separation of proteins and peptides. This column, featuring unique particles, maintains sharp and efficient peak shapes even at high flow rates. With a unique particle structure that combines a porous silica surface thin phase and a hard silica core, it shortens the diffusion distance of proteins, enabling practical high-speed HPLC separations for peptides and proteins up to 500–1,000 kDa. 【Features】 ■ The Poroshell 300 column, bonded with StableBond phases (C18, C8, C3), exhibits excellent stability and sensitivity in TFA and formic acid mobile phases. ■ Usable at pH 2 to 11, it achieves unique separations and high selectivity. *For more details, please refer to the PDF document or feel free to contact us.

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Long-chain and cis-trans isomer analysis column

Long-chain and cis-trans isomer analysis column

There are examples of analysis for vitamin K1 isomers! It is suitable for reverse phase separation of geometric isomers and positional isomers.

The "Ascentis Express 160 Å C30 U/HPLC" is a column for the analysis of long-chain and cis-trans isomers. It is suitable for the reversed-phase separation of geometric isomers and positional isomers. There are examples of analysis including a comparison of separation behavior with C18, four types of tocopherols, five types of fat-soluble vitamins, and vitamin K1 isomers. [Analysis Examples] ■Comparison of separation behavior with C18 ■Four types of tocopherols ■Five types of fat-soluble vitamins ■Vitamin K1 isomers *For more details, please refer to the PDF document or feel free to contact us.

  • Chemicals
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ZORBAX column / Poroshell column

ZORBAX column / Poroshell column

Dramatic improvement in productivity! Flexibility and scalability of methods for low molecular weight and biomolecule analysis.

The "ZORBAX Columns / Poroshell Columns" are specially designed products for HPLC analysis with high productivity. The silica used is of extremely high purity, very robust, and highly uniform, providing the highest level of reliability. Additionally, one of the features is the extremely wide range of phases and column configurations that cater to diverse application needs. 【Features of ZORBAX Columns】 ■ Excellent options and flexibility for low molecular weight and reversed-phase biomolecule analysis with over 18 phases, including Eclipse Plus and HILIC ■ Easy method development that demonstrates excellent performance across a wide range of target compounds and conditions ■ Improvement of UHPLC methods ■ Outstanding peak shape performance due to proven innovative silica and bonding technology ■ Long-term reliability by having the necessary options available when needed for analysis and preparative purification *For more details, please refer to the PDF materials or feel free to contact us.

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UHPLC Emitter Column "Aurora Series"

UHPLC Emitter Column "Aurora Series"

Robust column design. It can reduce loading and balancing time while increasing the identification count.

The "Aurora Series" is a UHPLC emitter column designed and manufactured to eliminate all dead volume at the column inlet and outlet. It maximizes the sample separation capability of chromatography packing materials. Additionally, it can be connected without the need for cumbersome and time-consuming adapters for fittings. 【Features】 ■ Reduces loading and equilibration time while increasing the number of identifications ■ Achieves excellent reproducibility ■ Robust column design ■ Enables maximum peptide identification *For more details, please refer to the PDF document or feel free to contact us.

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Reverse-phase chiral column ULTRON ES series protein stationary phase

Reverse-phase chiral column ULTRON ES series protein stationary phase

To everyone seeking chiral analysis under reverse phase conditions!

ULTRON ES-OVM is designated as an evaluation column for Clopidogrel bisulfate and Escitalopram oxalate in the United States Pharmacopeia (USP). It also corresponds to the ovomucoid chemically bonded amino silica gel described in the Japanese Pharmacopoeia (JP). ■ULTRON ES-OVM (USP L57) It uses ovomucoid, which is resistant to denaturation, as the ligand. 〈Product Lineup〉 ULTRON ES-OVM ULTRON ES-OVM-3 can be used for UHPLC and LC/MS ULTRON ES-OVM-C for shipping inspection with Clopidogrel bisulfate (USP compliant) ULTRON ES-OVM-E for shipping inspection with Escitalopram oxalate (USP compliant) ■ULTRON ES-PEPSIN It uses pepsin, a polypeptide-degrading enzyme, as the ligand. It is effective for the chiral separation of β-blockers.

  • Analytical Equipment and Devices
  • Separation device
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